Metabolic Pathway Peptides
5-Amino 1MQ — 50mg
$89
This product is intended for research purposes only. Not intended for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you acknowledge that you are a qualified researcher and understand the nature of this product.
5-Amino 1MQ (5-amino-1-methylquinolinium) is a small-molecule quinolinium salt, not a peptide, that inhibits the enzyme nicotinamide N-methyltransferase (NNMT); supplied as 50mg of lyophilized powder.
Metabolic Pathway PeptidesOverview
5-Amino-1-methylquinolinium is a methylated quinoline derivative carrying a permanent positive charge on the ring nitrogen and an amino substituent at position 5. It is a small molecule rather than a peptide, though it is catalogued alongside peptide products owing to its similar lyophilized presentation.
Its molecular target, NNMT, catalyzes transfer of a methyl group from S-adenosylmethionine to nicotinamide, yielding 1-methylnicotinamide and S-adenosylhomocysteine. In vitro, inhibition of this reaction alters intracellular concentrations of nicotinamide and S-adenosylmethionine in cells expressing the enzyme.
Mechanism of Action
Inhibits nicotinamide N-methyltransferase, the enzyme that transfers a methyl group from S-adenosylmethionine to nicotinamide; in vitro this shifts intracellular nicotinamide and S-adenosylmethionine concentrations in enzyme-expressing cells.
Certificates of Analysis1
Independent third-party lab reports for this peptide. Each CoA can be verified against its accession number at the testing lab.
1 independent test by Freedom Diagnostics Testing
| Test | Result |
|---|---|
| Purity (HPLC) | 99.712% |
| Identity (MS) | Pass |
| Endotoxins (LAL) | Pass |
Lab: Freedom Diagnostics Testing
Accession: 2603200310 / 2603200311
Reports are verifiable against the issuing lab using the accession or batch identifier above.
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