Neuropeptides
Dihexa — 10mg
$66
This product is intended for research purposes only. Not intended for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you acknowledge that you are a qualified researcher and understand the nature of this product.
Dihexa is a small synthetic peptide, N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide, structurally derived from angiotensin IV and modified at both termini with lipophilic hexanoic groups.
NeuropeptidesOverview
Dihexa (N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide) is a synthetic peptide derived from angiotensin IV, a hexapeptide fragment of the renin-angiotensin system. Its N-terminal hexanoic acid and C-terminal aminohexanoic amide raise the lipophilicity of the molecule relative to the parent fragment and reduce its susceptibility to aminopeptidase and carboxypeptidase cleavage.
In cell-based assays Dihexa interacts with the hepatocyte growth factor / c-Met receptor system, binding HGF and potentiating c-Met receptor tyrosine kinase autophosphorylation and downstream signaling. The peptide is supplied as a lyophilized powder in a 10 mg vial.
Mechanism of Action
Dihexa binds hepatocyte growth factor and potentiates activation of the c-Met receptor tyrosine kinase, increasing receptor autophosphorylation and downstream signaling in cultured cells.
Certificates of Analysis1
Independent third-party lab reports for this peptide. Each CoA can be verified against its accession number at the testing lab.
1 independent test by Freedom Diagnostics Testing
| Test | Result |
|---|---|
| Purity (HPLC) | 98.536% |
| Identity (MS) | Pass |
| Endotoxins (LAL) | Pass |
Lab: Freedom Diagnostics Testing
Accession: 2603260148
Reports are verifiable against the issuing lab using the accession or batch identifier above.
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