Neuropeptides
Semax — 10mg
$45
This product is intended for research purposes only. Not intended for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you acknowledge that you are a qualified researcher and understand the nature of this product.
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) based on the ACTH(4-10) fragment with a C-terminal Pro-Gly-Pro extension, supplied as a lyophilized powder in a 10 mg vial.
NeuropeptidesOverview
Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a seven-residue analogue of the adrenocorticotropic hormone fragment ACTH(4-10). The Pro-Gly-Pro extension at the C-terminus alters stability toward aminopeptidase cleavage relative to the parent fragment. The material is a lyophilized white powder, soluble in water.
In vitro, Semax interacts with melanocortin receptors MC4 and MC5, inhibits enkephalinase, and upregulates BDNF and NGF transcripts in cultured neural cells. Cell-free assays also describe altered nucleation and elongation kinetics of amyloid beta fibril assembly. Each vial contains 10 mg.
Mechanism of Action
Interacts with melanocortin receptors MC4 and MC5 and inhibits enkephalinase in vitro; upregulates BDNF and NGF transcripts in cultured neural cells and alters amyloid beta fibril assembly kinetics in cell-free systems.
Certificates of Analysis1
Independent third-party lab reports for this peptide. Each CoA can be verified against its accession number at the testing lab.
1 independent test by Janoshik Analytical
| Test | Result |
|---|---|
| Purity (HPLC) | 99.714% |
| Identity (MS) | Pass |
| Endotoxins (LAL) | Not Tested |
Lab: Janoshik Analytical
Accession: U3LFSC4IBDT7
Reports are verifiable against the issuing lab using the accession or batch identifier above.
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