Neuropeptides

DSIP 4mg

$27

This product is intended for research purposes only. Not intended for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you acknowledge that you are a qualified researcher and understand the nature of this product.

DSIP is a linear nonapeptide with the sequence Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu and a molecular weight near 849 daltons, first characterized in 1977, supplied as 4mg of lyophilized powder.

DSIPNeuropeptides

Overview

DSIP is a nine-residue peptide containing no cysteine and therefore no disulfide bridge. Its sequence includes two acidic residues (Asp5 and Glu9) and a single N-terminal tryptophan, giving the molecule an acidic isoelectric point. No cognate receptor has been identified.

Reported molecular interactions are diffuse rather than tied to a single binding site and include corticotropin-releasing hormone signaling and opioid receptor pathways in cell-free and cultured-cell systems. The peptide is hydrolyzed rapidly by peptidases in vitro, and the lyophilized solid dissolves in water.

Mechanism of Action

No cognate DSIP receptor has been characterized; reported activity is distributed across corticotropin-releasing hormone signaling and opioid receptor pathways in cultured-cell systems, with no single high-affinity binding site established.

Certificates of Analysis

Independent third-party lab reports for this peptide. Each CoA can be verified against its accession number at the testing lab.

No certificate of analysis is currently published for DSIP. Published lab reports for other lots and compounds are available on the Lab Testing page.

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