Immune & Cellular Peptides
LL-37 — 5mg
$66
This product is intended for research purposes only. Not intended for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you acknowledge that you are a qualified researcher and understand the nature of this product.
LL-37 is a 37-amino acid cathelicidin-family peptide cleaved from the hCAP-18 precursor by proteinase-3, forming an amphipathic alpha-helix; supplied as 5mg of lyophilized powder.
Immune & Cellular PeptidesOverview
LL-37 is the cathelicidin peptide encoded by the CAMP gene, released by proteolytic cleavage of the hCAP-18 precursor. Its 37 residues fold into an amphipathic alpha-helix in which cationic and hydrophobic faces occupy opposite sides of the helix, giving the molecule affinity for anionic lipid bilayers.
In vitro, the peptide inserts into negatively charged model membranes and binds lipopolysaccharide, and it is an agonist at the formyl peptide receptor FPRL1 (FPR2). The material is supplied as a lyophilized powder soluble in aqueous buffer.
Mechanism of Action
Inserts into anionic lipid bilayers via its amphipathic helix, binds lipopolysaccharide, and acts as an agonist at the formyl peptide receptor FPRL1 (FPR2) in cultured cells.
Certificates of Analysis1
Independent third-party lab reports for this peptide. Each CoA can be verified against its accession number at the testing lab.
1 independent test by Freedom Diagnostics Testing
| Test | Result |
|---|---|
| Purity (HPLC) | 99.761% |
| Identity (MS) | Pass |
| Endotoxins (LAL) | Pass |
Lab: Freedom Diagnostics Testing
Accession: 2602110148 / 2602110149
Reports are verifiable against the issuing lab using the accession or batch identifier above.
Related Peptides
Other compounds in the immune & cellular peptides category.
Immune & Cellular PeptidesEpitalon
40mg
Epitalon is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly, a defined-sequence analogue of the pineal peptide preparation Epithalamin, supplied as a lyophilized powder in a 40 mg vial.
Immune & Cellular PeptidesThymosin Alpha-1
10mg
Thymosin Alpha-1 is a 28-amino acid acetylated peptide corresponding to a sequence secreted by thymic epithelial cells, supplied as a lyophilized powder in a 10 mg vial.
Immune & Cellular PeptidesSS-31
40mg
SS-31 is a cell-permeable tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) with alternating aromatic and basic residues that associates with cardiolipin in the inner mitochondrial membrane; supplied as a 40mg lyophilized vial.