Matrix & Growth-Factor Peptides
TB-500 — 10mg
$60
This product is intended for research purposes only. Not intended for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you acknowledge that you are a qualified researcher and understand the nature of this product.
A synthetic peptide corresponding to the actin-binding domain of thymosin beta-4, a 43-amino-acid intracellular protein, supplied as a lyophilized powder in a vial containing 10 mg.
Matrix & Growth-Factor PeptidesOverview
TB-500 is a synthetic peptide whose sequence corresponds to the actin-binding region of thymosin beta-4, a 43-residue intracellular protein of the beta-thymosin family. The fragment retains the acidic Ac-Ser-Asp-Lys-Pro motif of the parent molecule. The material is a white lyophilized powder that is soluble in water.
In vitro, the peptide binds monomeric G-actin and alters filament assembly kinetics. Cell-culture work also describes engagement of the integrin-linked kinase and Akt signaling axis. Supplied as 10 mg of lyophilized peptide per vial.
Mechanism of Action
Binds monomeric G-actin and modulates filament assembly kinetics in vitro. Cell-culture studies also report interaction with the integrin-linked kinase and Akt signaling axis.
Certificates of Analysis2
Independent third-party lab reports for this peptide. Each CoA can be verified against its accession number at the testing lab.
2 independent tests by Freedom Diagnostics Testing
| Test | Result |
|---|---|
| Purity (HPLC) | 99.36% |
| Identity (MS) | Pass |
| Endotoxins (LAL) | Pass |
Lab: Freedom Diagnostics Testing
Accession: 2605200155
Reports are verifiable against the issuing lab using the accession or batch identifier above.
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